Latifi started karting in 2009 at the age of 13 experiencing good success in his native Canada and in the USA. He moved to single-seaters in 2012, going straight into the Italian F3 Championship with one win. In 2013, he stepped up to the European competition and joined PREMA in 2014. His career proceeded to the Formula Renault 3.5 series and the GP2 Series, which turned into the FIA Formula 2 Championship. In 2019, Latifi finished as a runner-up, gaining access to the Super Licence. He moved to Formula 1 in 2020 and has raced for Williams ever since.